25 thg 12, 2014

Subjects susceptible to high cholesterol

The disease is essentially high cholesterol condition lipid metabolic disorders, the cause may be primary (hereditary) or secondary to other diseases. The disorders include: an increase in low molecular weight lipoprotein (LDL-c), reduced high molecular weight type (DHL-c), increased triglycerides, this change also makes cholesterol increased, so called high cholesterol patients.

 
The groups at risk for dyslipidemia include:
1. The target group of overweight, obesity, smoking, alcohol consumption, eat more foods containing fat will increase the amount of triglycerides in the blood are those with high-risk disease high blood fat (disorder blood fat). The skinny but if the diet is not healthy: alcohol use, smoking, eating more animal organ capable of fat in the blood disease.
Cholesterol is produced in the liver (80%) of the fatty acids from food supplements or other metabolic phases and 20% is supplied directly from the content of foods high chlesterol such as tallow, red meat (beef, pork), shrimp, pork heart, tripe, brains, eggs, coconut oil (vegetable oil, but more saturated fatty acids).
In this group due to excessive eating habits, fatty acids (materials to produce cholesterol) cholesterol and is taken into the body too much, increase infiltration into the arterial endothelium, although sometimes LDL-c concentration is not high.
The adjustment of diet towards reducing foods containing cholesterol and exercising regularly can prevent effective dyslipidemia.
2. The target group suffering from diabetes, nephrotic syndrome, hypothyroidism, chronic liver disease: In this group, the treatment of positive, good control of symptoms and complications have a positive impact on the dyslipidemia.
- In diabetes: Diabetes is a metabolic disorder of carbohydrates (sugar), accompanied by metabolic disorders of lipid (fat) and protein (protein). In the living body changes sugar - protein - fat intimate relationship with each other mutual support. The long-term metabolic disorder of a nature have led to a metabolic disorder of the two remaining substances. In this case, the lipid metabolic disorders is often degraded and reduced all kinds lipoproten blood, but sometimes other types of LDL-c reduction but not decrease, or increase should cause dyslipidemia .
- In nephrotic syndrome: Nephrotic syndrome is a clinical syndrome and biochemistry, is characterized by edema, proteinuria (protein in the urine), high blood protein decreased, dyslipidemia and diabetes that can lipids, due to many different medical conditions cause. Here dyslipidemia is a symptom of nephrotic syndrome.
- In patients hypothyroidism: Thyroid thyroid hormone production is not sufficient cause tissue damage and metabolic disorders, including lipid metabolism. The biochemical tests for hypothyroidism common: anemia, increased cholesterol, increased triglycerides, glucose decreased, blood sodium decreased ....
3. The target group for chronic illness using long-term therapy is not the right way: Some cardiovascular drugs such as beta-blockers sympathetic, long-term birth control pills, alcohol,
- In alcoholics: Ethanol Alcohol is addictive, expression is dependent on the symptoms appear when no alcohol, the alcohol addiction forced to cut these symptoms.
Ethanol at high concentrations in the blood often cause tissue damage, ethanol mixed in between two layers of lipid molecules to reduce the order of the acyl chains of phospholipids alter membrane structure thereby increasing infiltration cholesterol on arterial endothelial increased atherosclerosis. Alcohol does not directly cause disease dyslipidemia, they are factors that increase the complications of dyslipidemia. Alcohol-related dyslipidemia because they cause chronic hepatitis and alcoholic cirrhosis, thereby leading to metabolic substances including lipid metabolism disorders.
- On the use of beta blockers (beta-blockers) long:
The beta-blockers are used in the treatment of cardiovascular diseases, eye (glaucoma patients), idiopathic run, thyroid toxicity, paroxysmal hypertension .... Some fat-soluble beta-blockers and they increase insulin resistance so easy to activate latent diabetes leads to diabetes, metabolic disorders and related lines are lipid metabolism. Therefore, patients must be treated as long-term medication must adhere to strict procedures set out by the doctor, not voluntary drug treatment, believing his longtime illness experienced patients.
- In the use of long-term birth control pills, drug is a combination of hormonal endocrine sex, long-term use is often accompanied by complications such as hyperpigmentation in cheek (melasma), gallstones , metabolic disorders including lipid metabolism.

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