25 thg 12, 2014

Hypercholesterolemia


Cholesterol is a fatty substance has an important role in the cell membrane and the components that make up a number of hormones. When too much cholesterol in the blood, it can form the deposition of fat clogs arteries, increasing the risk of heart attack and stroke.

Dangerous blood cholesterol increased
Signs and symptoms
For high blood lesteron not cause symptoms. A blood test is the only way to detect this condition.
Cause
- Inactive, obese and unhealthy diets contribute to LDL "bad" cholesterol and decrease HDL
"good" cholesterol.
- The field of genetic causes cells not remove LDL cholesterol from the blood or cause the liver to produce too much cholesterol.
Tests and diagnosis
Blood tests check cholesterol levels
- Total cholesterol: ≥ 240mg / dL.
- LDL cholesterol: ≥ 160 mg / dL.
- HDL cholesterol: ≤ 40 mg / dL.
- Triglycerides: ≥ 200 mg / dL
For accurate results, do not eat or drink anything (except water) for 9-12 hours before blood sampling.
Treatment
Lifestyle changes: eat a healthy diet, regular physical activity and avoidance of tobacco.
Medication:
- The statins. Have the effect of inhibiting substances that the liver needs to make cholesterol and help re-absorption of cholesterol from the arteries deposited in the city. This class consists of atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Altoprev, Mevacor), pravastatin (Pravachol), rosuvastatin (Crestor), and simvastatin (Zocor).
- The bile acid binding resin, including cholestyramine (Prevalite, Questran), colesevelam (WelChol) and colestipol (Colestid) reduce cholesterol indirectly via binding to bile acids, causing the liver to use excess cholesterol to make more bile acids, thanks it reduces cholesterol in the blood.
- Cholesterol absorption inhibitors such as ezetimibe (Zetia), often used in combination with statins
If you have high triglycerides in the blood, can be treated by:
- The drug fibrat groups, such as fenofibrate (Lofibra, Tricor) and gemfibrozil (Lopid) reduce the production of ultra-low-density lipoprotein cholesterol (VLDL) in the liver and accelerate the elimination of triglycerides from the blood.
- Niacin (Niaspan) limiting production of LDL and VLDL in the liver cholestero
Prevent
- Reduce excess weight
- Choose healthy foods is beneficial for the heart.
- Exercise regularly
- No smoking.

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